Christian Pulisic returned to Chelsea this week on crutches, according to manager Thomas Tuchel.
Tuchel, on the other hand, believes the American winger will be out for only 10 days.
Pulisic limped out after 62 minutes of his country’s 4-1 triumph against Honduras in a World Cup qualifier on Wednesday.
The 22-year-old returned to London on Thursday and will be unavailable for Saturday’s Premier League match against Aston Villa at Wembley.
In addition, he is expected to miss Chelsea’s Champions League group stage match against Zenit St Petersburg on Tuesday.
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“Unfortunately, Christian arrived on crutches yesterday, and he has an ankle injury that will keep him out for roughly 10 days,” Tuchel stated.
Chelsea will also be missing N’Golo Kante this weekend due to an ankle injury that kept him out of France’s international matches earlier this month, but he might play Zenit.